• Chandraprakash Umapathy, Mahesh Gajendran, Rupinder Mann, Umesha Boregowda, Thimmaiah Theethira, Sherif Elhanafi, Abhilash Perisetti, Hemant Goyal, and Shreyas Saligram.
• Department of Gastroenterology and Hepatology, University of California San Francisco, Fresno, CA 93721, USA.
• Dis Mon. 2020 Nov 1; 66 (11): 100986.

AbstractPancreatic fluid collections (PFC), including pancreatic pseudocysts and walled-off pancreatic necrosis, are a known complication of severe acute pancreatitis. A majority of the PFCs remain asymptomatic and resolve spontaneously. However, some PFCs persist and can become symptomatic. Persistent PFCs can also cause further complications such as the gastric outlet, intestinal, or biliary obstruction and infection. Surgical interventions are indicated for the drainage of symptomatic sterile and infected PFCs. Management of PFCs has evolved from a primarily surgical or percutaneous approach to a less invasive endoscopic approach. Endoscopic interventions are associated with improved outcomes with lesser chances of complications, faster recovery time, and lower healthcare utilization. Endoscopic ultrasound-guided drainage of PFCs using lumen-apposing metal stents has become the preferred approach for the management of symptomatic and complicated PFCs.Copyright © 2020 Elsevier Inc. All rights reserved.

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