Ugeskrift for laeger
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In clinical trials a single dose of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine has shown a rapid antidepressant effect in patients with treatment-resistant depression and bipolar depression. The implications of glutaminergic mechanisms in depression and the rapid effect of a single dose of ketamine could open new pathways to understand the pathophysiology of depression and the development of novel rapid-acting antidepressant drugs.
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Ugeskrift for laeger · Sep 2013
Case Reports[Acute pulmonary embolism and cardiac arrest treated with thrombolysis and an automatic chest compression device].
Survival after pulseless electrical activity cardiac arrest is poor. In this case report we describe a patient who had acute massive pulmonary embolism and was treated with thrombolysis and an automatic mechanical chest compression device, Lund University Cardiac Arrest System (LUCAS 2). Chest compressions were effectively provided for two hours during a prolonged resuscitation and transferral for pulmonary embolectomy. The patient was extubated one day after the operation and discharged with normal cerebral function nine days after the cardiac arrest.