Journal of veterinary emergency and critical care
-
J Vet Emerg Crit Care (San Antonio) · Feb 2009
Thrombelastography in 26 healthy horses with and without activation by recombinant human tissue factor.
To develop a standardized technique for thrombelastography (TEG) analysis in healthy adult horses, with and without the ex vivo addition of tissue factor (TF) as an activator. To determine reference intervals for TEG parameters in the horse, and to determine if traditional coagulation tests correlate with TEG. ⋯ TF-TEG using the described protocol may minimize variability in data obtained across institutions or users. However, due to the variability associated with different operators, it is recommended that each laboratory set up individual reference intervals with the personnel who will perform the assay, and that the assay protocols and data obtained are compared on a regular basis.
-
J Vet Emerg Crit Care (San Antonio) · Feb 2009
Comparison of viscoelastic coagulation analysis and standard coagulation profiles in critically ill neonatal foals to outcome.
To determine if changes in viscoelastic variables are associated with abnormalities observed in the standard coagulation profile and patient outcome in foals with suspected septicemia. ⋯ Viscoelastic coagulation evaluation could be used in a neonatal intensive care unit setting to further characterize coagulopathy, and identify foals at higher risk for poor outcome.
-
J Vet Emerg Crit Care (San Antonio) · Feb 2009
Preliminary evaluation of hemostasis in neonatal foals using a viscoelastic coagulation and platelet function analyzer.
To compare coagulation and platelet function parameters measured using a viscoelastic analyzer in 3 groups: foals presenting to a neonatal intensive care unit with presumed sepsis, normal foals, and adult horses. ⋯ Healthy foals differ in values measured by the viscoelastic coagulation and platelet function analyzer compared with healthy adult horses. ACT and CR abnormalities were more likely to be observed in foals with positive blood cultures. The viscoelastic coagulation and platelet function analyzer may be useful in identifying early hemostasic and platelet dysfunction in critically ill foals, particularly those that are septic.