Journal of veterinary emergency and critical care
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J Vet Emerg Crit Care (San Antonio) · Mar 2015
Randomized Controlled TrialA pilot study comparing a protocol using intermittent administration of glargine and regular insulin to a continuous rate infusion of regular insulin in cats with naturally occurring diabetic ketoacidosis.
The goal of this pilot study was to compare regular insulin administered by continuous rate infusion (CRI) to an approach using insulin glargine and regular insulin administered intermittently. ⋯ Although further research is required, an approach using intermittent short- and long-acting insulin injections appeared to be an effective option for treatment of DKA in cats.
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To summarize current understanding of the mechanisms responsible for changes occurring during red blood cell (RBC) storage, collectively known as the storage lesion, and to review the biological and clinical consequences of increasing storage time of RBCs. ⋯ Storage of RBCs induces progressive biochemical, biomechanical, and immunologic changes that affect red cell viability, deformability, oxygen carrying capacity, microcirculatory flow, and recipient response. Most reports in the human and veterinary literature support the concept that there are deleterious effects of the RBC storage lesion, but additional studies with improved experimental design are needed to identify compelling reasons to modify current blood banking and transfusion practices.
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J Vet Emerg Crit Care (San Antonio) · Mar 2015
A novel severity scoring system for dogs with heatstroke.
To develop a statistically-derived scoring system that can aid in severity assessment and outcome prediction for dogs with heatstroke. ⋯ The proposed models are applicable, allowing objective assessment of the severity and prognosis of heatstroke in dogs; however, they should be validated further in an independent cohort, and used cautiously for assessment of individual cases.
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J Vet Emerg Crit Care (San Antonio) · Mar 2015
Retrospective evaluation of risk factors and outcome predictors in cats with diabetic ketoacidosis (1997-2007): 93 cases.
To determine risk factors and outcome predictors in cats with diabetic ketoacidosis (DKA). ⋯ Cats with DKA are more likely to be Siamese than cats with uncomplicated DM. Poor outcome of cats with DKA is associated with increased initial creatinine, BUN, total magnesium, and total bilirubin concentrations. Good outcome was associated with a higher concentration of IV insulin CRI.