Journal of veterinary emergency and critical care
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J Vet Emerg Crit Care (San Antonio) · Jun 2010
Evaluation of an indirect oscillometric blood pressure monitor in normotensive and hypotensive anesthetized dogs.
To determine the accuracy and precision of an oscillometric noninvasive blood pressure device as a predictor of invasive direct blood pressure in healthy anesthetized hypotensive and normotensive dogs. ⋯ The oscillometric device was not reliably predictive of intra-arterial BP during hypotension associated with acute hemorrhage.
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J Vet Emerg Crit Care (San Antonio) · Jun 2010
High-mobility group box 1 as a surrogate prognostic marker in dogs with systemic inflammatory response syndrome.
To evaluate various surrogate markers associated with the inflammatory and counter-inflammatory responses with respect to mortality in dogs with systemic inflammatory response syndrome (SIRS). ⋯ Increases in plasma HMGB1 concentration and the ratio of HMGB1 to IL-10 may predict poorer outcomes in dogs with SIRS. The approach described may lead to reliable prognostic biomarkers and new therapeutic concepts in the study of SIRS in dogs.
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J Vet Emerg Crit Care (San Antonio) · Apr 2010
Comparative StudyComparison of ultrasonic Doppler flow monitor, oscillometric, and direct arterial blood pressure measurements in ill dogs.
To compare blood pressure measurements obtained via ultrasonic Doppler flow monitor (DOP) and 2 oscillometric noninvasive blood pressure monitors (CAR and PAS) to invasive blood pressure (IBP) in hospitalized, conscious dogs with a range of blood pressures. ⋯ The noninvasive blood pressure monitors in our study did not meet the validation standards set in human medicine. However, CAR diastolic and MAP measurements within the normotensive group, CAR MAP measurements within the hypertensive group, and PAS diastolic measurements in all groups were close to these standards. All indirect measurements showed greater bias during hypotension. Precision was poorer for all indirect systolic measurements than for MAP.
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J Vet Emerg Crit Care (San Antonio) · Apr 2010
ReviewControversies related to red blood cell transfusion in critically ill patients.
To review the evolution of and controversies associated with allogenic blood transfusion in critically ill patients. ⋯ RBC transfusion is unequivocally indicated for treatment of anemic hypoxia. However, critical hemoglobin or Hct below which all critically ill patients require transfusion has not been established and there are inherent risks associated with allogenic blood transfusion. Clinical trials designed to evaluate the effects of RBC age and leukoreduction on veterinary patient outcome are warranted. Implementation of evidence-based transfusion guidelines and consideration of alternatives to allogenic blood transfusion are advisable.