Journal of veterinary emergency and critical care
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J Vet Emerg Crit Care (San Antonio) · Jul 2018
Evaluation of pulse pressure variation and pleth variability index to predict fluid responsiveness in mechanically ventilated isoflurane-anesthetized dogs.
To evaluate whether pulse pressure variation (PPV) and pleth variability index (PVI) are more accurate than central venous pressure (CVP) for predicting fluid responsiveness in mechanically ventilated isoflurane-anesthetized dogs after premedication with acepromazine. ⋯ PPV and PVI predicted fluid responsiveness more accurately than CVP and may be useful to guide fluid administration in mechanically ventilated isoflurane-anesthetized dogs after premedication with acepromazine.
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J Vet Emerg Crit Care (San Antonio) · Mar 2018
ReviewClinical use of plasma lactate concentration. Part 1: Physiology, pathophysiology, and measurement.
To review the current literature with respect to the physiology, pathophysiology, and measurement of lactate. ⋯ The etiology of hyperlactatemia is complex and multifactorial. Understanding the relevant pathophysiology is helpful when characterizing hyperlactatemia in clinical patients.
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J Vet Emerg Crit Care (San Antonio) · Jan 2018
Retrospective evaluation of the prognostic utility of plasma lactate concentration, base deficit, pH, and anion gap in canine and feline emergency patients.
To determine the association of plasma lactate concentration, pH, base deficit (BD), and anion gap (AG) in dogs and cats on presentation to an emergency room with outcome, and to compare the prognostic significance of hyperlactatemia with a concurrent metabolic acidosis with that of hyperlactatemia and a normal metabolic acid-base balance. ⋯ The presence and magnitude of hyperlactatemia on presentation to the emergency room may help identify dogs and cats with high likelihood of in-hospital mortality, and the presence of lactic acidosis specifically may help identify dogs with yet higher risk of in-hospital mortality.
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J Vet Emerg Crit Care (San Antonio) · Jan 2018
Observational StudyThe influence of inflammation and hematocrit on clot strength in canine thromboelastographic hypercoagulability.
To investigate parameters causing canine thromboelastographic hypercoagulability and to investigate whether thromboelastography (TEG) with Cytochalasin D (Cyt D) added is related to parameters of platelet activity. ⋯ Overall clot strength in TEG analyses of the hypercoagulable dogs included in the present study appears to be primarily associated with inflammation as well as hematocrit. Furthermore, the ratio between standard TEG analyses and TEG analyses with Cyt D may reflect some degree of platelet activity.
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J Vet Emerg Crit Care (San Antonio) · Nov 2017
Influence of catecholamines at different dosages on the function of the LiDCO sensor in isoflurane anesthetized horses.
To compare the lithium dilution method for cardiac output (LiDCO) and bolus-thermo-dilution (BTD) measurements before and during infusion of dobutamine, dopamine, phenylephrine, or noradrenaline at 2 different doses in anesthetized horses and to examine the correlation between sensor voltages (saline-blood exposed) and possible measurement errors. ⋯ This study demonstrated that catecholamines could lead to overestimation in a dose-dependent fashion in LiDCO measurements. Monitoring changes in sensor voltage differences (saline-blood) is a valuable and clinically applicable tool to predict errors in LiDCO measurements.