Arthritis research & therapy
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Arthritis Res. Ther. · Mar 2011
Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis.
There has been no report in the literature of a soluble form of interleukin (IL)-18 receptor α (IL-18Rα). In this study, we evaluated the levels and characteristics of soluble IL-18Rα (sIL-18Rα) in the sera of patients with rheumatoid arthritis (RA) and compared these results to control populations. ⋯ The sIL-18Rα complex could be a potentially useful biomarker for the diagnosis of RA.