Chinese medical journal
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Chinese medical journal · Apr 2022
Meta AnalysisRisk of infections of biological and targeted drugs in patients with spondyloarthritis: meta-analysis of randomized clinical trials.
Concerns exist regarding the risk of infections in patients with spondyloarthritis (SpA) treated with biologics. We assessed the risk of infections of biological and targeted drugs in patients with SpA by performing a meta-analysis based on randomized controlled trials (RCTs). ⋯ This meta-analysis shows that biological therapy in patients with SpA may increase the risk of infections, including serious infections, URTI, nasopharyngitis, and Candida infection, which should be paid attention to in our clinical practice.
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Chinese medical journal · Apr 2022
Diabetes mellitus promoted lymph node metastasis in gastric cancer: a 15-year single-institution experience.
Previous studies have revealed that diabetes mellitus (DM) promotes disease progress of gastric cancer (GC). This study aimed to further investigating whether DM advanced lymph nodes (LNs) metastasis in GC. ⋯ DM was an independent risk factor for promoting LN metastasis. The preponderance of LN involvement in the DM group was aggravated with the advancement of tumor depth.