Pediatric blood & cancer
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Pediatric blood & cancer · Nov 2008
The morbidity and mortality of pediatric oncology patients presenting to the intensive care unit with septic shock.
Children with an underlying diagnosis of malignancy are at high risk for developing serious infections. Previous studies, although very limited in number, suggest a particularly poor outcome for these patients if admitted to an intensive care unit with septic shock. ⋯ This review found that the survival of oncology patients admitted to the PICU with septic shock was not significantly different from control patients, and was significantly higher than previous reports. Aggressive management of these children is warranted as their long term prognosis may be much more favorable than originally thought.
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Pediatric blood & cancer · Nov 2008
Randomized Controlled TrialPediatric oncology sedation trial (POST): A double-blind randomized study.
There is limited evidence to support the use of an anti-emetic with the administration of intra-thecal chemotherapy. Nor is there adequate clarity on analgesic strategies for children with cancer undergoing painful procedures. ⋯ This study provides evidence that the addition of an analgesic (fentanyl) and an anti-emetic (ondansetron) to the combination of a sedative (midazolam) and an anesthetic (propofol) is of measurable benefit in children who undergo procedures that are painful and risk the consequence of nausea and vomiting.