Pediatric blood & cancer
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Pediatric blood & cancer · Aug 2013
Randomized Controlled Trial Clinical TrialPrompt administration of antibiotics is associated with improved outcomes in febrile neutropenia in children with cancer.
Time-to-antibiotic (TTA) administration is a widely used quality-of-care measure for children with cancer and febrile neutropenia (FN). We sought to determine whether TTA is associated with outcomes of FN. ⋯ TTA and presentation to the ED are independently associated with poor outcomes of FN.
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Pediatric blood & cancer · Aug 2013
Multicenter Study Clinical TrialPedsQL™ sickle cell disease module: feasibility, reliability, and validity.
Sickle cell disease (SCD) is an inherited chronic disease that is characterized by complications such as recurrent painful vaso-occlusive events that require frequent hospitalizations and contribute to early mortality. The objective of the study was to report on the initial measurement properties of the new PedsQL™ SCD Module for pediatric patient self-report ages 5-18 years and parent proxy-report for ages 2-18 years. ⋯ The PedsQL™ SCD Module demonstrated acceptable measurement properties. The PedsQL™ SCD Module may be utilized in the evaluation of SCD-specific health-related quality of life in clinical research and practice. In conjunction with the PedsQL™ Generic Core Scales and the PedsQL™ Multidimensional Fatigue Scale, the PedsQL™ SCD Module will facilitate the understanding of the health and well-being of children with SCD.