Singapore medical journal
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Singapore medical journal · Sep 2024
Determinants of decision-making in biopsy of PI-RADS 3 transition zone lesions.
Cancer rates for Prostate Imaging-Reporting and Data System (PI-RADS) 3 lesions are low. We aimed to determine the clinical and magnetic resonance imaging (MRI) parameters that can provide risk stratification for PI-RADS 3 transition zone (TZ) lesions to guide decision for biopsy, which can improve the cost-effectiveness of resource utilisation. ⋯ Clinical parameters (PSAD and PHI) and MRI features (lesion size, DWI score, lesion location) can be used to risk stratify PI-RADS 3 TZ lesions and guide decision for targeted biopsy.
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Singapore medical journal · Sep 2024
Utility of photoplethysmography in detecting elevated blood glucose among non-diabetics.
This study aimed to evaluate a technique of using photoplethysmography (PPG) for detecting elevated blood glucose in individuals. ⋯ This study shows that a non-invasive method of assessing diabetes mellitus risk using PPG combined with demographics is a viable option to provide a cheaper and more accessible modality for population-wide diabetes mellitus risk assessment.
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Singapore medical journal · Sep 2024
Femoral and tibial phenotypes of varus alignment in a Southeast Asian arthritic population: a descriptive study.
Knowledge of femoral and tibial morphology is important for patient-specific surgery in both joint reconstruction and preservation procedures. Studies evaluating morphological variance in femoral and tibial alignments in Asian populations are scarce. This is the first descriptive study evaluating the femoral and tibial phenotypes of varus alignment in a Southeast Asian population. ⋯ The findings of this study will be important to surgeons during planning for joint preservation procedures (such as corrective osteotomies) and joint arthroplasties to restore alignment.
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Singapore medical journal · Sep 2024
Comparison of two different preload targets of stroke volume variation during kidney transplantation: a randomised controlled trial.
Maintaining adequate preload during kidney transplantation (KT) is important for graft function. We evaluated whether a high or low normal target for a dynamic preload index of stroke volume variation (SVV) would impact graft function during living donor KT. ⋯ Our randomised trial demonstrated that an SVV target of either 6% or 12% could be adequate as a preload management target for postoperative graft function during living donor KT. However, given the low incidence of DGF in living donor KT and type II error, our study should be interpreted carefully and further studies for deceased donor KT are required.