Medicina
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Coronary involvement in COVID-19 infection usually presents as type 2 acute myocardial infarction (AMI), due to increased 02 consumption and reduction of oxygen supply, and less frequently as type 1 (STEMI). In that cases, thrombogenicity of the infection may contribute to acute coronary occlusion. ⋯ Both were treated by direct angioplasty using pharmacologic stent. Discussion is related to treatment of AMI at discharge, if anticoagulation should be added to double antiplatelet therapy, and if any prophylactic antithrombotic treatment should be considered at discharge from COVID-19 pneumonia in some patients.
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Research about the academic profile of students with Autism Spectrum Disorder (ASD) reports a variable performance, although it tends to be lower than what it is expected according to the cognitive level. In the school context, reading and writing are crucial abilities for learning in different curricular areas and they have important implications for academic, social and occupational success. A brief review is carried out about the main reading and writing disabilities that students with ASD show. ⋯ However, a lower performance in reading comprehension and, particularly, inferential comprehension has been frequently described. In addition, deficits in the different components of writing have been reported, especially, handwriting and text coherence. Different factors may explain this profile of difficulties, like linguistic factors or aspects related to the psychological theories of autism, which may contribute to possible interventions.
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Due to the coronavirus disease 2019 (COVID-19) pandemic, a wide number of compounds are under scrutiny regarding their antiviral activity, one of them being hydroxychloroquine. Cardiac aspects of the use of chloroquine and hydroxychloroquine are reviewed in this manuscript. ⋯ We found an anti-inflammatory effect with reduction of longterm cardiovascular events, a very infrequent heart disease due to a lysosomal effect of the drug, and at the hemodynamic level hypotension, tachycardia, and QT interval prolongation, exacerbated when combined with azithromycin. However, the rate of adverse cardiac events of hydroxychloroquine (and chloroquine) was low.
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Multicenter Study Observational Study
Type 2 diabetes. Prevalence of hypoglycemia in public versus private health care system.
Social vulnerability has proved to be an independent risk factor for hypoglycemia in patients with diabetes. In some countries, patients who are in a vulnerable situation are assisted in the public health system which provides free medical care. This study compares the prevalence of hypoglycemia among patients with type 2 diabetes (T2D), in public versus private sector and its relationship with social vulnerability. ⋯ Similarly, unemployment (OR 5.04 95% CI 2.69-9.46), and marginal SEL (OR 60.79 95% CI 14.89-248.13) increased the risk of hypoglycemia. Several factors related to social vulnerability as unemployment, marginal SEL and poor sanitary education showed a significant increase in the hypoglycemia risk. Professionals working with people with diabetes must take into account these factors for a safe treatment of the disease.