Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · May 2010
Review[Thirtieth anniversary of world health organization's world wide smallpox eradication].
This year in May, the World Health Assembly will celebrate the thirtieth anniversary of world wide Smallpox eradication. For this reason we report on this program's vertices.
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In Austria activities against smallpox started with variolation, the artificial infection with the smallpox virus, which bore the risk of contracting the disease. In 1800, Lower Austria was the first country in continental Europe to implement Edward Jenner's invention of vaccination with cowpox for mass vaccination. In the beginning vaccination was practised by inoculation from one human being to another. In this paper development of smallpox vaccination from the beginning to it's cessation in 1981 is described.
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Wien. Klin. Wochenschr. · May 2010
Randomized Controlled Trial Comparative StudyPreoperative synbiotic bowel conditioning for elective colorectal surgery.
Preoperative bowel cleaning for elective colorectal surgery is a routine procedure. Synbiotics (probiotics plus prebiotics) are known for their beneficial effects on gut immune function and maintenance of the gut barrier. The main purpose of this study was to replace preoperative mechanical bowel cleaning with synbiotics and to assess the systemic inflammatory response and clinical outcome in patients undergoing colorectal surgery. ⋯ Preoperative administration of prebiotics in elective colorectal surgery appears to have the same protective effect in preventing a postoperative inflammatory response as mechanical bowel cleaning. Further prospective studies are needed to verify the effects of synbiotics.
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Wien. Klin. Wochenschr. · May 2010
Randomized Controlled Trial Comparative StudyEffects of pregabalin on acute herpetic pain and postherpetic neuralgia incidence.
Acute zoster pain usually disappears with regression of the rash but may be of significant intensity and prolonged duration leading to postherpetic neuralgia. We evaluated the effect of pregabalin on alleviation of acute zoster pain and onset of postherpetic neuralgia. ⋯ The study did not prove any statistically significant effect of pregabalin in pain relief in patients with acute zoster pain or in the onset of postherpetic neuralgia in comparison with the placebo. The use of pregabalin was related to a statistically significant increase in the appearance of adverse effects.
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Wien. Klin. Wochenschr. · May 2010
Influence of body position on hemodynamics in patients with ischemic heart disease undergoing cardiac surgery.
The cardiovascular response to decreased or increased preload in high-risk patients with ischemic heart disease enables us to understand the physiologic response to hemorrhage and its treatment. Although numerous studies have failed to show its effectiveness, the head-down position is still widely used to treat patients with hypotension and shock. The aim of our study was to evaluate the influence of body position on hemodynamics in high-risk patients undergoing coronary artery bypass graft surgery. ⋯ The results of our study showed a hemodynamic response similar to hemorrhage after placing the patients in a 20 degrees head-up position and improving hemodynamics in the head-down position in mechanically ventilated patients undergoing coronary artery bypass graft surgery.