International journal of dermatology
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A 32-year-old Thai woman developed acquired hypertrichosis lanuginosa with generalized lanugo hair, deeply furrowed tongue, and keratosis pilaris. She had metastatic adenocarcinoma of the liver. A review of world literature reveals 24 cases of which 22 were associated with proven malignancies. Acquired hypertrichosis lanuginosa is almost always a cutaneous sign of internal cancer.
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Historical Article
International Society of Tropical Dermatology in perspective.
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Systemic blastomycosis may rarely involve the larynx, and it most likely is a result of hematogenous dissemination or direct inoculation from a currently or previously active pulmonary infection. Often, laryngeal blastomycosis has been confused with squamous cell carcinoma because of the clinical and histopathologic similarities, and this confusion has led to inaccurate diagnosis and inappropriate therapy. The etiologic agent, Blastomyces dermatiditis, may be seen in infected tissue with routine and special stains; however, cultural proof remains the sine qua non for diagnosis.