European journal of clinical investigation
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Eur. J. Clin. Invest. · Dec 2002
Randomized Controlled Trial Comparative Study Clinical TrialClinical and genetic features underlying the response of patients with bronchial asthma to treatment with a leukotriene receptor antagonist.
Treatment with antileukotriene drugs results in clinical improvement in many, though not all, patients with asthma. It can be hypothesized that the subpopulation of asthmatic patients, characterized by aspirin intolerance and cysteinyl-leukotriene overproduction, might profit most from antileukotriene treatment. ⋯ No difference in the clinical response to the montelukast treatment was observed between the AIAs and the ATAs.