European journal of clinical investigation
-
Eur. J. Clin. Invest. · Jan 2009
Measurement of nasal nitric oxide: evaluation of six different sampling methods.
Specific guidelines are developed for the measurement of bronchial FE(NO), however, nasal nitric oxide (nNO) measurement is not standardised yet, resulting in divergent nNO values. This study compares six different sampling methods for nNO as described in the literature, to analyse their outcome and short term and long term reproducibility. ⋯ Different methods result in different levels and reproducibility of nNO. In regard to this, methods of humming and breath holding are recommended for standardised measurement of nasal NO.