Lancet
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Randomized Controlled Trial Multicenter Study
Usual versus tight control of systolic blood pressure in non-diabetic patients with hypertension (Cardio-Sis): an open-label randomised trial.
The level to which systolic blood pressure should be controlled in hypertensive patients without diabetes remains unknown. We tested the hypothesis that tight control compared with usual control of systolic blood pressure would be beneficial in such patients. ⋯ Boehringer-Ingelheim, Sanofi-Aventis, Pfizer.