JAMA : the journal of the American Medical Association
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A breast pathology diagnosis provides the basis for clinical treatment and management decisions; however, its accuracy is inadequately understood. ⋯ In this study of pathologists, in which diagnostic interpretation was based on a single breast biopsy slide, overall agreement between the individual pathologists' interpretations and the expert consensus-derived reference diagnoses was 75.3%, with the highest level of concordance for invasive carcinoma and lower levels of concordance for DCIS and atypia. Further research is needed to understand the relationship of these findings with patient management.