The Journal of family practice
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Describe the multiple symptoms of irritable bowel syndrome (IBS) and their impact on quality of life. Use a staged strategy for the diagnostic evaluation of IBS based on history and physical examination, including Rome IV criteria. Individualize treatment for IBS based on an evolving understanding of pathophysiologic mechanisms using evidence-based therapies to address patient concerns and improve quality of life.
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Apply evidence-based diagnostic guidelines for patients who have clinical features consistent with insomnia. Use evidence-based guidelines to develop comprehensive treatment plans that include cognitive-behavioral therapy, pharmacologic treatment, and combination therapies to achieve optimal outcomes Identify basic elements of cognitivebehavioral therapy for insomnia Differentiate among medications FDA-approved for treating insomnia by discussing mechanism of action, safety, efficacy, and use.
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Identify the benefits and limitations of statin therapy as a treatment option for lowering LDL-C. Intensify treatment in appropriate patients or refer for intensification. Describe the safety and efficacy of ezetimibe, bempedoic acid, PCSK9 inhibitors, LDL apheresis. Describe the safety and efficacy of medications in late-stage development or under review by the FDA for LDL-C reduction.