The New England journal of medicine
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Letter Case Reports
Treatment of brain metastases of malignant melanoma with temozolomide.
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The independent prognostic value of elevated jugular venous pressure or a third heart sound in patients with heart failure is not well established. ⋯ In patients with heart failure, elevated jugular venous pressure and a third heart sound are each independently associated with adverse outcomes, including progression of heart failure. Clinical assessment for these findings is currently feasible and clinically meaningful.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Effect of prone positioning on the survival of patients with acute respiratory failure.
Although placing patients with acute respiratory failure in a prone (face down) position improves their oxygenation 60 to 70 percent of the time, the effect on survival is not known. ⋯ Although placing patients with acute respiratory failure in a prone position improves their oxygenation, it does not improve survival.