Investigative ophthalmology & visual science
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Invest. Ophthalmol. Vis. Sci. · Nov 1997
A new method for studying the selective adherence of blood lymphocytes to the microvasculature of human retina.
To develop a sensitive and reproducible technique for measuring the adherence of blood lymphocytes to vessel walls exposed in sections of human retina and for examining the role of lymphocyte and vascular adhesion molecules in these events. ⋯ This technique allows measurements to be made of lymphocyte adherence to vascular and nonvascular structures of retina ex vivo. Extension of this approach to the study of leukocyte adherence to sections of pathologic retina may be of clinical and experimental applicability in understanding mechanisms of retinal inflammation.