Investigative ophthalmology & visual science
-
Invest. Ophthalmol. Vis. Sci. · Aug 2001
Comparative StudySensations evoked by selective mechanical, chemical, and thermal stimulation of the conjunctiva and cornea.
To study the sensations evoked by selective mechanical, chemical, and thermal stimulation of the conjunctiva and compare them with those elicited by similar stimulation of the cornea. ⋯ Sensations evoked in the cornea by selective mechanical, chemical, and heat and cold stimulation always presented an irritation component. In the conjunctiva, stimuli of the same intensity are always perceived as less irritating than in the cornea. Cold and other non-noxious subqualities of sensation can be evoked in the conjunctiva.
-
Invest. Ophthalmol. Vis. Sci. · Aug 2001
The effects of intraocular injection of interleukin-13 on endotoxin-induced uveitis in rats.
Interleukin (IL)-13 is a strong immunomodulatory cytokine that inhibits macrophages from secreting proinflammatory mediators. This study was conducted to investigate the effect of intraocular injection of IL-13 on the development of endotoxin-induced uveitis (EIU) in the Lewis rat. ⋯ Injection of IL-13 into the anterior chamber may inhibit the ocular inflammation induced by LPS injection by reducing intraocular cytokine and chemokine mRNA expression in ocular tissues.