Investigative ophthalmology & visual science
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Invest. Ophthalmol. Vis. Sci. · Aug 2016
Functional and Morphologic Changes of Meibomian Glands in an Asymptomatic Adult Population.
The aim of the study was to understand natural changes of meibomian glands (MG) that occur with aging in the absence of any ocular pathology or ocular discomfort symptoms, to differentiate between "age normal" and pathologic or dysfunctional changes of the MG. ⋯ Progressive MG loss occurs normally with age accompanied by reduced quality and quantity of the meibum produced. However, clinical presentation of ocular discomfort symptoms is stalled without corresponding disruption to tear function.