Investigative ophthalmology & visual science
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Invest. Ophthalmol. Vis. Sci. · Jan 2017
Functional Properties of Sensory Nerve Terminals of the Mouse Cornea.
To define the firing properties of sensory nerve terminals innervating the adult mouse cornea in response to external stimuli of differing modality. ⋯ The mouse cornea is innervated by trigeminal ganglion (TG) neurons that respond to the same stimulus modalities as corneal receptors of other mammalian species. Mechano- and polymodal endings underlie detection of mechanical and chemical noxious stimuli while HB-LT and LB-HT cold thermoreceptors appear to be responsible for basal and irritation-evoked tearing and blinking, respectively.