Intensive care medicine
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Intensive care medicine · Feb 2002
Multicenter Study Comparative StudyEpidemiology of sepsis and infection in ICU patients from an international multicentre cohort study.
To examine the incidence of infections and to describe them and their outcome in intensive care unit (ICU) patients. ⋯ The crude incidence of ICU infections remains high, although the rate varies between ICUs and patient subsets, illustrating the added burden of nosocomial infections in the use of ICU resources.
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Intensive care medicine · Feb 2002
Multicenter StudyMortality associated with late-onset pneumonia in the intensive care unit: results of a multi-center cohort study.
To evaluate the attributable mortality associated with late-onset nosocomial pneumonia (LOP) while taking into account the severity at admission, the evolution of the patients during the first 4 days after admission to the ICU and the appropriateness of initial empiric antibiotic treatment. ⋯ These data suggest that, in addition to severity scores, the underlying medical conditions and the evolution of severity within the first 4 days in ICU, late-onset pneumonia independently contribute to ICU patient mortality when empirical antibiotic treatment is not immediately appropriate.
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Intensive care medicine · Feb 2002
Airway obstruction and ventilator dependency in young children with congenital cardiac defects: a role for self-expanding metal stents.
Young children with congenital cardiac defect and airway obstruction leading to ventilator dependency present a significant clinical challenge with uncertain outcome. ⋯ Airway stenting in such young children is an infrequent procedure often undertaken in dire circumstances. We have found it valuable in enabling ventilator-dependent children to be extubated with encouraging early results. Their long-term outlook remains uncertain and is dependent on the underlying cardiac status.
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Intensive care medicine · Feb 2002
Randomized Controlled Trial Clinical TrialPhysiological effects of constant versus decelerating inflation flow in patients with chronic obstructive pulmonary disease under controlled mechanical ventilation.
To study the cardiorespiratory effects of inspiratory flow rate and waveform in COPD patients. ⋯ Changing the ventilator in volume-controlled mode with a DF or CF profile has no significant cardiorespiratory effect in intubated COPD patients mechanically ventilated for acute respiratory failure.