Intensive care medicine
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Intensive care medicine · May 2020
Multicenter Study Observational StudyExtracorporeal membrane oxygenation for refractory cardiac arrest: a retrospective multicenter study.
The aim of this study was to assess the neurologic outcome following extracorporeal cardiopulmonary resuscitation (ECPR) in five European centers. ⋯ ECPR was associated with intact neurological recovery in 19% of unselected cardiac arrest victims, with 38% favorable outcome if stringent selection criteria would have been applied.
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Intensive care medicine · May 2020
Observational StudyIdentification and validation of biomarkers of persistent acute kidney injury: the RUBY study.
The aim of the RUBY study was to evaluate novel candidate biomarkers to enable prediction of persistence of renal dysfunction as well as further understand potential mechanisms of kidney tissue damage and repair in acute kidney injury (AKI). ⋯ Elevated urinary CCL14 predicts persistent AKI in a large heterogeneous cohort of critically ill patients with severe AKI. The discovery of CCL14 as a predictor of persistent AKI and thus, renal non-recovery, is novel and could help identify new therapeutic approaches to AKI.