Intensive care medicine
-
Intensive care medicine · Dec 2001
Comparative Study"Ideal PEEP" is superior to high dose partial liquid ventilation with low PEEP in experimental acute lung injury.
To determine the effects of a high dose partial liquid ventilation (PLV) approximating the amount of the functional residual capacity (FRC) with low levels of positive end-expiratory pressure (PEEP) compared to a lung-protective strategy with volume-controlled mechanical ventilation (vcMV) with a PEEP level above the lower inflection point (LIP) on pulmonary gas exchange, haemodynamics, respiratory mechanics and lung injury in an experimental model of acute lung injury (ALI). ⋯ In this porcine model of ALI, vcMV with a PEEP level of 1 cmH(2)O above the LIP was superior to high dose PLV with a PEEP of 5 cmH(2)O in improving gas exchange and lung mechanics. In terms of lung damage, the treatment in the (ideal) PEEP group resulted in the lowest total lung injury scores.
-
Intensive care medicine · Dec 2001
Reintubation after planned extubation in surgical ICU patients: a case-control study.
Risk factors of reintubation were studied after planned extubation in a surgical ICU. ⋯ The VAC mode of weaning of surgical ICU patients is associated with an increased incidence of reintubation and morbidity after planned extubation. This probably reflects the clinical condition of patients unable to tolerate pressure support.
-
Intensive care medicine · Dec 2001
Mask mechanics and leak dynamics during noninvasive pressure support ventilation: a bench study.
To study the mask mechanics and air leak dynamics during noninvasive pressure support ventilation. ⋯ P(mask-fit) and P(mask-occl) can be easily measured in pneumatic cushioned masks and the data obtained may be useful to guide mask fit and inspiratory pressure set during noninvasive positive pressure ventilation.
-
Intensive care medicine · Dec 2001
Case ReportsEnoxaparin-associated severe retroperitoneal bleeding and abdominal compartment syndrome: a report of two cases.
To describe a complication of low-molecular-weight heparin (enoxaparin) in the setting of critically ill patients. ⋯ High-risk patients receiving low-molecular-weight heparin should be identified and closely monitored to prevent serious bleeding complications.
-
Intensive care medicine · Dec 2001
Randomized Controlled Trial Comparative Study Clinical TrialEndocrine effects of dopexamine vs. dopamine in high-risk surgical patients.
To compare the endocrine effects of dopexamine and dopamine on prolactin (PRL), dihydroepiandrosterone sulfate (DHEAS), cortisol, thyrotropin (TSH), and peripheral thyroid hormone serum concentrations in surgical patients at risk of developing postoperative complications because of hypoperfusion of various organ systems. ⋯ Routine postoperative optimizing of men undergoing abdominal surgical procedures with dopexamine at higher doses or dopamine induces at least partial hypopituitarism, which may possibly affect postoperative morbidity.