The International journal of artificial organs
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Having examined the various disadvantages of the catheterization of the central veins performed using the Seldinger technique, we report our results of internal jugular vein catheterization under echographic guidance in 38 uremic patients. The echographic guidance technique allows an easier and safer utilization of the internal jugular vein as vascular access in emergency situations.
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Randomized Controlled Trial Clinical Trial
Contact, coagulation and platelet interaction with heparin treated equipment during heart surgery.
Heparin coating of an extracorporeal device may reduce blood activation. To evaluate protein and platelet interaction with Duraflo II surface treatment of the cardiopulmonary bypass (CPB) circuit, thirty coronary artery bypass grafting patients were randomly divided into two groups (Duraflo II, n = 15 or Control, n = 15). Binding of antibodies against factor XII, antithrombin III (ATIII) and platelet receptor GpIb were significantly higher (p < 0.01) on the Duraflo II treated surface. ⋯ During the second phase of CPB, after release of the aortic crossclamp, factor XII and thrombin were strongly activated in both groups indicated by a sharp increase in concentrations of T/AT complex as well as FPA. Platelet numbers tended to increase more in the control group during CPB than in the Duraflo II group, likely by interaction of platelet GpIb receptors on the Duraflo II treated surface (p < 0.01). However, platelet activation assessed by beta-TG was similar in both groups of patients.(ABSTRACT TRUNCATED AT 250 WORDS)