Journal of the American Academy of Dermatology
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We report a second case of perforating lichen nitidus. This supports the occurrence of the transepidermal elimination phenomenon in lichen nitidus and justifies the addition of lichen nitidus to the family of perforating dermatoses.
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J. Am. Acad. Dermatol. · Jul 1983
Case ReportsNecrotizing vasculitis within cutaneous lesions of mycosis fungoides.
Mycosis fungoides is a T cell lymphoma with a predilection for cutaneous involvement. This paper describes the clinical manifestations and histopathologic features of a case of mycosis fungoides with necrotizing vasculitis localized to the lesions of cutaneous lymphoma. ⋯ The large numbers of perivascular malignant helper T lymphocytes may have induced immunoglobulin synthesis, resulting in the formation of these complexes followed by deposition in vessel walls and subsequent necrotizing vasculitis. Possible alternative mechanisms include the presence of anti-T cell antibodies, or cytotoxic effector cells.
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A retrospective study demonstrated that fourteen of twenty-eight patients (50%) with clinical, histologic, and immunofluorescent findings of bullous pemphigoid had peripheral blood eosinophilia. Blood eosinophilia ranged from 5% to 43% when first tested, with increase in one patient to 56% during treatment. The pathophysiologic cause of blood eosinophilia in bullous pemphigoid is discussed with its relationship to previously demonstrated elevations of IgE and eosinophilic chemotactic factor of anaphylaxis (ECF-A) in serum and blister fluid. Peripheral blood eosinophilia was a common finding in our group of patients, and bullous pemphigoid should be included in the differential diagnosis of bullous skin conditions with eosinophilia.
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J. Am. Acad. Dermatol. · Mar 1982
Case ReportsToxicodendron radicans dermatitis with black lacquer deposit on the skin.
Four patients with clinical Toxicodendron dermatitis (poison ivy) presented with dramatic black lacquer-like deposits on several lesions. This black deposit was also observed at sites of injury on poison ivy plants and was reproduced on volunteers by the application of plant sap on the skin. Histologically, the observed material was identified in the stratum corneum. This little-recognized phenomenon has been mentioned in past dermatologic literature.
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J. Am. Acad. Dermatol. · Dec 1981
The National Association of Insurance Commissioners (NAIC) Medical Malpractice Closed Claim Study 1975-1978. A review of dermatologic claims.
The National Association of Insurance Commissioners (NAIC) Medical Malpractice Closed Claim Study 1975-1978 is the first major uniform nationwide survey of its kind. A total of 71,782 closed claims were reviewed during a 3 1/2-year period. ⋯ A review of the dermatologic closed claims with indemnity payments included in the study revealed that dermatologists accounted for 127 claims representing 0.7% of total paid claims, with payments totaling +2,549,125 representing 0.6% of total indemnity dollars paid. Since our specialty represents 1.4% of all practicing physicians, it is clear that the NAIC study reaffirms dermatology as being among the lowest malpractice risk specialties.