The Journal of infection
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The Journal of infection · Mar 2010
Monocyte HLA-DR expression as predictor of poor outcome in neonates with late onset neonatal sepsis.
Down regulation of HLA-DR expression on monocytes has been reported in adult sepsis. The aims of this study were, first to evaluate monocyte HLA-DR expression in late onset neonatal infection and second to investigate the prognostic value of monocyte HLA-DR expression at onset of symptoms for the final outcome. ⋯ According to our findings, monocyte HLA-DR expression seems to be an early predictive marker for the prognosis in late onset neonatal sepsis.