The Journal of infection
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The Journal of infection · Mar 2017
Network visualization for outbreak response: Mapping the Ebola Virus Disease (EVD) chains of transmission in N'Zérékoré, Guinea.
During the 2014-2015 Ebola Virus Disease (EVD) outbreak in N'Zérékoré, Forested Guinea, modes of transmission remained unexamined for a number of new cases. We used network visualization to investigate EVD transmission chains (TC) in seven sub-prefectures of N'Zérékoré in order to adapt outbreak response. ⋯ Network visualization during field response is crucial in enhancing local control strategies, refining outbreak response and aiding rapid response teams in insuring psychosocial and socio-economic recovery. Urban settings need to focus on reducing hospital EVD transmission whereas rural settings should focus on raising awareness of transmission within a household and safeguarding EVD burials.
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The Journal of infection · Feb 2017
Intensive care unit-acquired pneumonia due to Pseudomonas aeruginosa with and without multidrug resistance.
Pseudomonas aeruginosa often presents multi-drug resistance (MDR) in intensive care unit (ICU)-acquired pneumonia (ICUAP), possibly resulting in inappropriate empiric treatment and worse outcomes. We aimed to identify patients with ICUAP at risk for these pathogens in order to improve treatment selection and outcomes. ⋯ Pseudomonas aeruginosa remains the most frequent aetiology of ICUAP, with high prevalence of MDR. These risk factors should be taken into account to avoid inappropriate empiric antibiotics for Pa-ICUAP. Pseudomonas aeruginosa, regardless multidrug resistance, was not associated with different propensity-adjusted survival.
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The Journal of infection · Feb 2017
Observational StudyMolecular diagnosis of bloodstream infections in onco-haematology patients with PCR/ESI-MS technology.
Onco-haematological patients are prone to develop infections, and antibiotic prophylaxis may lead to negative blood cultures. Thus, the microbiological diagnosis and subsequent administration of a targeted antimicrobial therapy is often difficult. The goal of this study was to evaluate the usefulness of IRIDICA (PCR/ESI-MS technology) for the molecular diagnosis of bloodstream infections in this patient group. ⋯ PCR/ESI-MS offers a reliable identification of pathogens directly from whole blood. While additional studies are needed to confirm our findings, the system showed a lower sensitivity in onco-haematological patients in comparison with previously reported results in patients from the Intensive Care Unit.
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The Journal of infection · Feb 2017
Retraction Of PublicationRetraction notice to: Validity of existing CD 4+ classification in North Indians, in predicting immune status [J Infect 51 (2005) 41-46].
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). It was brought to the attention of the Editor-in-Chief that large sections of the abstract, methods and results and discussion of the paper are identical to a paper published in The National Medical Journal of India, Volume 14, Issue 6, November/December 2001, Pages 335-339. http://archive.nmji.in/archives/Volume-14/issue-6/original-articles-2.pdf We apologise to the readers of the journal that this plagiarism was not detected during the submission process. To verify originality, all articles submitted to the Journal of Infection are now checked by the originality detection service CrossCheck.
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The Journal of infection · Jan 2017
Estimating the burden of invasive and serious fungal disease in the United Kingdom.
The burden of fungal disease in the UK is unknown. Only limited data are systematically collected. We have estimated the annual burden of invasive and serious fungal disease. ⋯ Uncertainty is intrinsic to most burden estimates due to diagnostic limitations, lack of national surveillance systems, few published studies and methodological limitations. The largest uncertainty surrounds IA in critical care patients. Further research is needed to produce a more robust estimate of total burden.