The Journal of infection
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The Journal of infection · Jun 2010
Case ReportsParadoxical vision loss associated with optochiasmatic tuberculoma in tuberculous meningitis: a report of 8 patients.
Paradoxical appearance of new or expansion of existing optochiasmatic tuberculoma, leading to severe vision loss, is a devastating complication in patient with tuberculous meningitis. ⋯ Prompt recognition of paradoxical optochiasmatic tuberculoma with the help of vision assessment and neuroimaging is vital for patient's life and vision. Paradoxical reactions should not be labeled as a new or resistant infection. The prior treatment schedule should continue, and dexamethasone may be added or its dose enhanced.
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The Journal of infection · May 2010
Review Meta AnalysisNeutrophil CD64 expression as marker of bacterial infection: a systematic review and meta-analysis.
We performed a systematic review and meta-analysis of studies to evaluate the diagnostic accuracy of expression of CD64 on polymorphonuclear neutrophils (PMN) as a marker for bacterial infection. ⋯ On the basis of this meta-analysis, CD64 expression on PMNs could be a useful diagnostic cell-based parameter of bacterial infections. However, published studies about this topic showed a low methodological quality.
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The Journal of infection · Mar 2010
Monocyte HLA-DR expression as predictor of poor outcome in neonates with late onset neonatal sepsis.
Down regulation of HLA-DR expression on monocytes has been reported in adult sepsis. The aims of this study were, first to evaluate monocyte HLA-DR expression in late onset neonatal infection and second to investigate the prognostic value of monocyte HLA-DR expression at onset of symptoms for the final outcome. ⋯ According to our findings, monocyte HLA-DR expression seems to be an early predictive marker for the prognosis in late onset neonatal sepsis.
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The Journal of infection · Feb 2010
Review Comparative StudyValidation and comparison of SCAP as a predictive score for identifying low-risk patients in community-acquired pneumonia.
(1) To validate the Severe Community Acquired Pneumonia (SCAP) score in predicting 30-day mortality. (2) To validate its ability to identifying patients at low risk of death. (3) To compare it against the Pneumonia Severity Index (PSI), and the British Thoracic Society's CURB-65 rules. ⋯ The SCAP is valid to predict 30-day mortality among low-risk patients and identifies a larger proportion of patients as low-risk than the other studied rules.