Journal of clinical gastroenterology
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J. Clin. Gastroenterol. · Sep 2009
Randomized Controlled TrialPropofol alone versus propofol in combination with meperidine for sedation during colonoscopy.
Despite the increasing popularity of propofol for sedation in colonoscopy, the optimal regimen is still controversial. Both propofol alone and propofol in combination with meperidine are frequently used during colonoscopy, but the impact of adding meperidine has not been evaluated. This study aimed to investigate if adding meperidine to propofol offers any advantage in terms of patient tolerance, recovery time, and postcolonoscopy discomforts. ⋯ For sedated colonoscopy, propofol in combination with meperidine is better than propofol alone in improving patients' tolerance and recovery.