The Journal of asthma : official journal of the Association for the Care of Asthma
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Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) is a poorly understood disease with an increasing morbidity and mortality. Currently, the most effective treatment for ACOS is unknown and omalizumab for ACOS has not yet been reported. ⋯ Our study shows that omalizumab may be an effective and safe therapy for patients with ACOS. However larger randomized trials are needed.