American journal of kidney diseases : the official journal of the National Kidney Foundation
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Review Meta Analysis
Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis.
Acute kidney injury (AKI) is common in hospitalized patients. The impact of AKI on long-term outcomes is controversial. ⋯ The development of AKI, defined as acute changes in serum creatinine level, characterizes hospitalized patients at increased risk of long-term adverse outcomes.
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Randomized Controlled Trial Comparative Study
Sodium citrate versus heparin catheter locks for cuffed central venous catheters: a single-center randomized controlled trial.
Sodium citrate has antibacterial and anticoagulant properties that are confined to the catheter when used as a catheter lock. Studies of its use as a catheter lock have suggested its efficacy in preventing infection and bleeding complications compared with sodium heparin. ⋯ Widespread and long-term use of 46.7% citrate catheter locks with Tesio-Cath access is not justified by this study.
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Comparative Study
Rapid reversal of acute kidney injury and hospital outcomes: a retrospective cohort study.
Acute kidney injury (AKI), defined as an increment in serum creatinine level of 0.3 mg/dL or greater in 48 hours, is associated with poor outcomes. The prognosis associated with an increased creatinine level, either on admission or that develops in the hospital (ie, AKI), that rapidly returns to normal is not known. ⋯ An increase in serum creatinine level of 0.3 mg/dL or greater during 48 hours of hospitalization predicts outcomes even if the value returns to normal. Patients who present to the hospital with an increased creatinine level that returns rapidly to normal have outcomes approaching those with serum creatinine levels consistently in the normal range.