Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
-
Graefes Arch. Clin. Exp. Ophthalmol. · Mar 2014
Randomized Controlled TrialHigher optic nerve sheath diameters are associated with lower ocular blood flow velocities in glaucoma patients.
To investigate the relationship between optic nerve sheath diameter (ONSD) and retrobulbar blood flow velocities, as measured by color Doppler imaging (CDI) in glaucoma patients. ⋯ ONSD is negatively correlated with retrobulbar blood flow velocities in glaucoma patients, but not in healthy controls.
-
Graefes Arch. Clin. Exp. Ophthalmol. · Mar 2014
Multicenter StudyAssessment of functional and morphometric endpoints in patients with non-arteritic anterior ischemic optic neuropathy (NAION).
The primary objective of this bi-center explorative pilot study was the quantitative assessment of visual field defects and retinal nerve fiber layer thickness (RNFT) over 6 months in patients with acute non-arteritic anterior ischemic optic neuropathy (NAION), in order to elucidate the natural course of NAION and provide a reference dataset for future treatment studies. ⋯ Functional deficits were present directly after onset of NAION and did not change relevantly further on. Morphological changes comprise severe swelling after onset of NAION, which rapidly turns into atrophy. Already after 2 months more than 80 % of the patients showed a RNFT below normal limits. Progressive RNFL thinning between month 2 and month 4 suggests ongoing atrophy, whereas a stable morphologic end point is reached after month 4.