The American journal of emergency medicine
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Am J Emerg Med
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Sickle cell disease (SCD) is characterized by microvascular occlusion which leads to multiorgan damage, including left ventricular diastolic dysfunction. Left ventricular diastolic dysfunction has been shown to be an independent risk factor for death in SCD patients. Left atrial dilation (LAD) has been used as a surrogate marker for identification of left ventricular diastolic dysfunction. ⋯ LAD was associated with higher ED utilization, lower hemoglobin level, and more hemolysis in patients with SCD.