Journal of perinatology : official journal of the California Perinatal Association
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Comparative Study
Postnatal lactate as an early predictor of short-term outcome after intrapartum asphyxia.
To compare the predictive value of pH, base deficit and lactate for the occurrence of moderate-to-severe hypoxic ischaemic encephalopathy (HIE) and systemic complications of asphyxia in term infants with intrapartum asphyxia. ⋯ The highest recorded lactate level in the first hour of life and serial measurements of lactate are important predictors of moderate-to-severe HIE.
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This study assessed the experiences of bereaved parents of multiples with resuscitation and life-support discussions, the death process, and conversations with health-care professionals about death. ⋯ Multiple-birth parents' choices resemble those of singleton parents at the end of an infant's life.
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Case Reports
Bilateral cataracts, retinal detachment and vitreous hemorrhage in a newborn with congenital diaphragmatic hernia.
Congenital diaphragmatic hernia (CDH) is associated with a wide range of other malformations. We describe a patient with CDH who also had significant eye findings noted at birth.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
This study compares pyridoxine-metoclopramide combination therapy to prochlorperazine and promethazine monotherapies in the outpatient treatment of nausea and vomiting in pregnancy. ⋯ Combination therapy with pyridoxine and metoclopramide appears to be superior to either monotherapy in the treatment of nausea and vomiting in pregnancy.
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Randomized Controlled Trial Comparative Study Clinical Trial
Randomized trial of normal saline versus 5% albumin for the treatment of neonatal hypotension.
This study was designed to assess the comparative efficacy of normal saline (NS) and 5% albumin (ALB) for treatment of hypotension in the acutely ill newborn. ⋯ NS was shown to be as effective as ALB for the correction of acute hypotension in the newborn infant. Given comparable efficacy of NS, along with its relatively low cost and availability, it should be considered the initial treatment of choice in this setting.