Critical care clinics
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This article presents an overview of the benefits and efficacy of transesophageal echocardiography (TEE) in the critically ill patient. The echocardiographic evaluation of ventricular function both regional and global, is discussed with special emphasis on ischemic heart disease; assessment of preload, interrogation of valvular heart disease (prosthetic and native) and its complications; endocarditis and its complications; intracardiac and extracardiac masses, including pulmonary embolism; aortic diseases (e.g., aneurysan, dissection, and traumatic tears); evaluation of patent foramen ovale and its association with central and peripheral embolic events; advancements in computer technology; and finally, the effect of TEE on critical care.
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In summary, newer imaging technologies yield three-dimensional pictures of the left ventricle. Detailed information is provided on regional wall motion, wall thickening, and ventricular volumes, which can be helpful in managing patients with cardiac disease. MR imaging gives the highest resolution images, and MR angiography can be invaluable in assessing the anatomy of an aortic dissection. ⋯ First pass RNA is probably the most accurate method for measuring RVEF and can be performed at the bedside using a portable multicrystal camera. Serial measurements of RVEF may be helpful in managing patients with pulmonary hypertension of various causes. For patients with documented acute myocardial infarction or chest pain and no acute myocardial necrosis or for patients undergoing preoperative risk assessment, combined perfusion and function using nuclear techniques yields both stress-induced ischemia and resting ventricular function in a single procedure and is timely and cost effective.
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NIRS is an attractive monitoring technology because it is a noninvasive, real-time, repeatable method that allows for regional assessment of the adequacy of tissue oxygenation. It is able to evaluate the oxygenation state of hemoglobin in tissue and redox state of cyt a1,a3, which reflects the overall activity of oxidative metabolism in the cells. The primary technical limitation of current technology is the inability to measure accurately the optical pathlength online, limiting the ability to quantify precisely concentrations of oxygen-dependent chromophores. Even with this limitation, NIRS can provide unique and valuable in vivo metabolic information without invasive intervention.
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Critical care clinics · Oct 1996
ReviewPulmonary artery catheters in the critically ill. An overview using the methodology of evidence-based medicine.
Evidence-based approaches to assessing the clinical literature are used increasingly in issues relating to critical care medicine. As we discussed previously, this approach attempts to provide a logical and convenient framework from which the quality and relevance of clinical studies may be assessed in an unbiased manner. An evidence-based approach also allows the reader to differentiate between solid evidence and evidence that is based on a presumed mechanism, standard practice, or conventional wisdom. ⋯ However, what this exercise has taught us is that there is little objective evidence to support this conclusion. The challenge to critical care practitioners is not only to apply the evidence-based processes more frequently to our environment but also to use the information to separate out clearly what is fact versus opinion. Where there is little evidence to support a particular clinical practice, as we have demonstrated with the PAC review earlier, the challenge to the clinician should be the design and conduct of clinical trials clarifying debate between opinion and evidence.
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In the quest for a better monitor of end-organ injury in the critically ill patient, gastrointestinal tonometry to measure intramucosal pH (pHi) and PCO2 has been advocated by several investigators. The authors discuss the principles and practice of gastric tonometry. ⋯ Although prognostic capability is an important role for tonometry, the principal benefit of the technology is its efficacy as an index of tissue resuscitation and as a guide to medical intervention. Given recent technical advances, gastrointestinal tonometry may gain increasing use in the assessment of tissue perfusion and oxygen metabolism.