Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Oct 2010
Acceleration of diabetic wound healing by collagen-binding vascular endothelial growth factor in diabetic rat model.
Vascular endothelial growth factor (VEGF) is an important active protein for the induction of angiogenesis and plays an important role in the tissue regeneration of diabetic wounds. In this study, we used collagen-binding VEGF in a diabetic rat model to investigate the effects of this new method. ⋯ Topical application of CBD-VEGF can promote diabetic wound healing in rat model, which could potentially provide a better therapeutic option for diabetic wounds.