Diabetes research and clinical practice
-
Diabetes Res. Clin. Pract. · Feb 2010
Meta AnalysisAspirin for primary prevention of cardiovascular events in patients with diabetes: A meta-analysis.
To systematically review trials concerning the benefit and risk of aspirin therapy for primary prevention of cardiovascular events in patients with diabetes mellitus. ⋯ In patients with diabetes, aspirin therapy did not significantly reduce the risk of cardiovascular events without an increased risk of major bleeding, and showed sex-specific effects on MI and stroke.
-
Diabetes Res. Clin. Pract. · Feb 2010
Comparative StudyEvaluation and comparison of guidelines for the management of people with type 2 diabetes from eight European countries.
The most recent nationally recognised guidelines for type 2 diabetes from eight European countries (Belgium, England/Wales, France, Germany, Ireland, Italy, the Netherlands and Sweden) were compared. The Appraisal of Guidelines for Research and Evaluation (AGREE) instrument was used for quality assessment. Details of recommendations for key process and outcome indicators were also extracted. Appraisal and data extraction were conducted independently by two researchers. ⋯ Our findings suggest that there are some areas of good practice relating to guideline development where more attention is needed. Despite a substantial degree of consensus for specified targets, observed differences at detailed level suggest a lack of consistency in relation to some aspects of the information provided to clinicians across Europe.