Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Aug 2012
Randomized Controlled Trial Multicenter StudyEffect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes.
Liraglutide reduces bodyweight in patients with type 2 diabetes mellitus (T2DM). This study aimed to investigate the mechanisms underlying this effect. ⋯ Liraglutide caused decreased gastric emptying and increased reduction in bodyweight. The mechanisms of the liraglutide-induced weight-loss may involve a combined effect on energy intake and energy expenditure.
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Diabetes Res. Clin. Pract. · Aug 2012
Diabetes care: Opinions, needs and proposed solutions of Swiss patients and healthcare professionals: a qualitative study.
To explore, both among patients with diabetes and healthcare professionals, opinions on current diabetes care and the development of the "Regional Diabetes Program". ⋯ Patients and professionals pointed out similar problems and solutions but explored them differently. Combined with coming quantitative data, these results should help to further develop, adapt and implement the "Regional Diabetes Program".
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Diabetes Res. Clin. Pract. · Aug 2012
Clinical implication of urinary tubular markers in the early stage of nephropathy with type 2 diabetic patients.
The aim of this study was to evaluate the association of urinary tubular markers, interleukin-18 (IL-18) and angiotensinogen with albuminuria in early nephropathy of type 2 diabetics. ⋯ The results of this study suggest that urinary tubular markers may be independently associated with albuminuria in the early stage of nephropathy in type 2 diabetics (eGFR ≥ 60 mL/min/1.73 m(2)) and may reflect inflammatory processing and the activation of the intrarenal RAS.
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Diabetes Res. Clin. Pract. · Jun 2012
Case ReportsDiabetic ketoacidosis accompanied by hypothermia: a case report.
Diabetic ketoacidosis (DKA) is an acute, life-threatening complication of diabetes mellitus and is caused by insulin insufficiency. Hypothermia is defined as a core temperature of less than 35°C and is sometimes accompanied by DKA. We report two patients with diabetes who were admitted for DKA accompanied by hypothermia.