The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Mar 2002
Comparative StudyEvaluation of diagnostic tests for influenza in a pediatric practice.
Recent advances in the diagnosis and treatment of influenza virus infections include: (1) rapid bedside diagnosis methods with simple commercially available tests; and (2) Food and Drug Administration approval of treatment for children 1 year of age and older with neuraminidase inhibitor drugs. For proven benefit antivirals should be used within 2 days of onset of symptoms. ⋯ In this first head-to-head comparison of four rapid diagnostic tests for influenza, Directigen Flu A, Quickvue and Flu OIA appear equivalent in sensitivity, specificity, positive predictive value and negative predictive value. Z Stat Flu was not as sensitive or as efficient as the other three tests.
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Pediatr. Infect. Dis. J. · Mar 2002
Randomized Controlled Trial Comparative Study Clinical TrialCefepime versus ceftazidime as empiric monotherapy for fever and neutropenia in children with cancer.
Monotherapy with cefepime or ceftazidime is an effective alternative to combination therapy for the treatment of febrile neutropenic adult cancer patients. We compared the efficacy and safety of cefepime and ceftazidime as empiric monotherapy of febrile neutropenia in children with cancer. ⋯ Cefepime appeared to be as effective and safe as ceftazidime for empiric treatment of febrile episodes in neutropenic pediatric cancer patients.
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Pediatr. Infect. Dis. J. · Mar 2002
Clinical TrialVoriconazole in the treatment of aspergillosis, scedosporiosis and other invasive fungal infections in children.
To describe the safety and efficacy of voriconazole in children treated within the compassionate release program. ⋯ These data support the use of voriconazole for treatment of invasive fungal infections in pediatric patients who are intolerant of or refractory to conventional antifungal therapy.