The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Apr 2000
Risk factors for candidemia in Neonatal Intensive Care Unit patients. The National Epidemiology of Mycosis Survey study group.
Candida species are important nosocomial pathogens in neonatal intensive care unit (NICU) patients. ⋯ Candida spp. are an important cause of late onset sepsis in NICU patients. The incidence of candidemia might be decreased by the judicious use of treatments identified as risk factors and avoiding H2 blockers.
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Pediatr. Infect. Dis. J. · Apr 2000
Comparative Study Clinical Trial Controlled Clinical TrialEffect of rapid diagnosis on management of influenza A infections.
Few studies have examined the impact of rapid viral diagnostic tests on patient management. ⋯ The detection of influenza A by EIA has a positive impact on medical management by decreasing antibiotic use in pediatric patients evaluated in an ED, by decreasing the duration of antibiotic use in hospitalized patients and by encouraging antiviral therapy.
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Pediatr. Infect. Dis. J. · Mar 2000
Inhaled corticosteroid therapy is safe in tuberculin-positive asthmatic children.
Although treatment with oral corticosteroids can cause reactivation of latent Mycobacterium tuberculosis (TB) infection in purified protein derivative (PPD)-positive individuals with no evidence of clinical disease, little is known about the effects of inhaled corticosteroids in this respect. ⋯ Long term inhaled budesonide therapy appears to be safe in PPD-positive asthmatic children.
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Pediatr. Infect. Dis. J. · Mar 2000
Comparative StudyUmbilical vein interleukin 6 and tumor necrosis factor alpha plasma concentrations in the very preterm infant.
To examine the relationship between umbilical vein plasma concentrations of interleukin 6 (IL-6) and tumor necrosis factor (TNF)-alpha and early neonatal sepsis in the very preterm infant, and the histopathologic findings of chorioamnionitis in the placentas from these pregnancies. ⋯ An elevated umbilical vein IL-6 concentration is a good indicator of sepsis syndrome in the very preterm infant and also correlates with histologic chorioamnionitis in these pregnancies.