The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Feb 2007
Case ReportsAtovaquone and azithromycin treatment for babesiosis in an infant.
An 8-month-old infant with cyanotic heart disease and transfusion-associated Babesia microti infection is reported here. At initial presentation, she was ill appearing, febrile and cyanotic. ⋯ The infant was treated successfully with a combination of oral azithromycin and atovaquone. This combination is an alternative to clindamycin and quinine for the treatment of children with babesiosis.
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Pediatr. Infect. Dis. J. · Feb 2007
Immunogenicity and safety of a second dose of measles-mumps-rubella-varicella vaccine in healthy children aged 5 to 6 years.
Two doses of measles-mumps-rubella (MMR) vaccine are recommended for elimination of these diseases in countries with universal mass vaccination; a 2-dose program is also likely to be required for elimination of childhood varicella and has recently been provisionally recommended in the United States. Given the overlap in MMR and varicella vaccination schedules, development of a combined vaccine appears logical and would facilitate the introduction of 2 doses of varicella vaccination in healthy children with no additional injections. ⋯ This experimental tetravalent MMRV vaccine appears well suited for use in national immunization programs in place of a second dose of MMR or MMR plus varicella in children who have already received a first dose of MMR.
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Pediatr. Infect. Dis. J. · Feb 2007
Lack of value of procalcitonin for prediction of coronary aneurysms in Kawasaki disease.
We studied the clinical, biologic (white blood cells, C-reactive protein and procalcitonin) and echocardiographic findings in 18 children hospitalized for Kawasaki disease from January 1999 until February 2006 to determine if procalcitonin is a useful marker to predict coronary aneurysms. In our study, contrary to earlier reports, elevated procalcitonin was not correlated with development of coronary aneurysms.
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Mycetoma is a chronic infection caused by aerobic actinomycetes and filamentous fungi. It is an occupational disease frequent in tropical countries and is uncommon in children. ⋯ Mycetomas are exceptional in children; in our setting, actinomycetomas are more frequent than eumycetomas. The clinical and microbiologic diagnosis is simple. Overall, treatment response is better for actinomycetomas than for eumycetomas.
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Pediatr. Infect. Dis. J. · Dec 2006
Impact of rapid viral testing for influenza A and B viruses on management of febrile infants without signs of focal infection.
The objective of this study was to assess the effect of rapid testing for influenza virus on management of febrile young infants. ⋯ The inclusion of rapid influenza testing for the evaluation of febrile young infants without signs of focal infection during influenza season decreases the need for additional studies and reduces the length of stay in the ED, the use of antibiotic treatment and unnecessary hospitalizations.