Critical care medicine
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Critical care medicine · Dec 1997
Comparative StudyImpact of different customization strategies in the performance of a general severity score.
To compare the impact of two different customization strategies in the performance of the admission Mortality Probability Model II (MPM II0) using formal statistical assessment. ⋯ In this ICU patient database, second-level customization was more effective than first-level customization in improving the overall goodness-of-fit of MPM II0 and should probably be chosen as the preferential strategy to improve the fit of a model when the sample size is large enough. However, second level customization had only a slight impact on discrimination. Its effects on the uniformity of fit are insufficient to overcome the problems that can arise when the model is applied in populations in which the case-mix is distinct from the population where it was originally developed.
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Critical care medicine · Dec 1997
Comparative StudyUse of intratracheal pulmonary ventilation versus conventional ventilation in meconium aspiration syndrome in a newborn pig model.
To determine whether intratracheal pulmonary ventilation (ITPV) allows for effective oxygenation and ventilation at lower mean airway pressures and peak inspiratory pressures than conventional ventilation in a piglet model of meconium aspiration syndrome. ⋯ These results indicate that ITPV can be used to effectively ventilate and oxygenate piglets with meconium aspiration syndrome at lower mean airway pressures and peak inspiratory pressures than conventional ventilation. This lower pressure causes less injury to the lungs of the animals.
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Critical care medicine · Dec 1997
Early bloodstream infection after cardiopulmonary bypass: frequency rate, risk factors, and implications.
To determine the incidence, predisposing factors, and outcome of early bloodstream infection after cardiopulmonary bypass. ⋯ Early bloodstream infection after cardiac surgery is uncommon and involves predominantly Gram-negative bacteria. The risk factors associated with bloodstream infection were preoperative morbidity and more complex surgery. Bloodstream infection was associated with a significantly adverse impact on outcome after cardiac surgery.