Critical care medicine
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Critical care medicine · May 1999
Augmented enhancement of in vitro production of inflammatory cytokines in peripheral blood mononuclear cells in patients undergoing simultaneous resection of the liver and gastrointestinal tract.
To determine changes in the production of inflammatory cytokines and acute-phase proteins, and in the priming of peripheral blood mononuclear cells (PBMC), as mechanisms for the high incidence of postoperative complications in patients who have undergone hepatectomy simultaneously with resection of the gastrointestinal tract. ⋯ The augmented enhancement of the priming of PBMC as a result of surgery in patients undergoing simultaneous resection of the liver and gastrointestinal tract, together with the reduced synthesis of the acute-phase reactants and impaired host defense mechanisms, might be responsible for the high incidence of postoperative complications, possibly because subsequent exposure of primed macrophages/monocytes to triggering substances such as endotoxin and bacterial components after operation results in inappropriate production of inflammatory cytokines.
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Critical care medicine · May 1999
Editorial Comment ReviewArterial puncture during central venous catheter insertion.
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Critical care medicine · May 1999
Prolonged partial liquid ventilation in spontaneously breathing awake animals.
To date, studies of partial liquid ventilation (PLV) have examined its effects acutely in anesthetized and mechanically ventilated subjects. We set out to develop a model of prolonged PLV in awake, spontaneously breathing animals. ⋯ Percutaneously assisted intratracheal cannulation with catheter exteriorization permits prolonged PLV in spontaneously breathing, unsedated animals. Continuous perfluorocarbon exposure with this method is reproducible, consistent, and well tolerated for 24 hrs in uninjured animals.
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Critical care medicine · May 1999
Editorial Comment ReviewBuffer treatment for cardiac resuscitation: putting the cart before the horse?
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Critical care medicine · May 1999
Editorial Comment ReviewCapnography in critical care: accurate assessment of ARDS therapy?