Critical care medicine
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Critical care medicine · May 2022
Hyperdynamic Left Ventricular Ejection Fraction in ICU Patients With Sepsis.
To evaluate the cause and prognosis of hyperdynamic left ventricular ejection fraction in critically ill patients with sepsis. ⋯ Hyperdynamic left ventricular ejection fraction was associated with mortality in septic ICU patients and may reflect unmitigated vasoplegia from sepsis. Depressed left ventricular ejection fraction was not associated with mortality but was associated with cardiovascular disease.
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Critical care medicine · May 2022
Neighborhood Socioeconomic Disadvantage and Disability After Critical Illness.
Factors common to socioeconomically disadvantaged neighborhoods, such as low availability of transportation, may limit access to restorative care services for critical illness survivors. Our primary objective was to evaluate whether neighborhood socioeconomic disadvantage was associated with an increased disability burden after critical illness. Our secondary objective was to determine if the effect differed for those discharged to the community compared with those discharged to a facility. ⋯ Neighborhood socioeconomic disadvantage is associated with a higher disability burden in the 12 months after a critical illness. Future studies should evaluate barriers to functional recovery for ICU survivors living in disadvantaged neighborhoods.
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Critical care medicine · May 2022
Randomized Controlled Trial Multicenter StudyEvaluating Vitamin C in Septic Shock: A Randomized Controlled Trial of Vitamin C Monotherapy.
To determine whether IV vitamin C therapy reduces 28-day mortality in patients with septic shock. ⋯ Vitamin C monotherapy failed to significantly reduce mortality in septic shock patients as hypothesized. Our findings do not support its routine clinical use for this purpose.