Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · Dec 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of two 1-week low-dose omeprazole triple therapies--optimal treatment for Helicobacter pylori infection?
To determine and compare the efficacy and tolerability of two 1-week regimen comprising omeprazole, clarithromycin and amoxycillin or metronidazole in the eradication of Helicobacter pylori, and to determine the influence of bacterial resistance to metronidazole and clarithromycin on the outcome of treatment. ⋯ Both the OAC and the OMC regimens were convenient and well-tolerated treatments for H. pylori. However, eradication rates were lower than anticipated.