Wiener medizinische Wochenschrift
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Wien Med Wochenschr · Jan 1999
Randomized Controlled Trial Multicenter Study Clinical TrialPAT--the Preventive Allergy Treatment Study design and preliminary results.
The Preventive Allergy Treatment Study, the PAT Study, is a European multi-center study. The end-point is to show in what capacity allergen specific subcutaneous immunotherapy can reduce the outcome of asthma in children with allergic rhinoconjunctivitis sensitized to birch and/or timothy pollen. Two hundred and ten children aged from 5 to 13 years were included in the study. ⋯ Preliminary data show that immunotherapy has been effective, it has been safe and statistically significantly less children in the actively treated group had asthmatic symptoms than children in the control group. Data have not been evaluated from all centers at the moment. The study is a prospective follow-up study, the patients' data will be evaluated next time in the year 2002.
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Fibromyalgia is a chronic soft tissue pain syndrome characterized by the presence of widespread musculosceletal aching, tender points at characteristic sites, fatigue and poor sleep. Associated disorders are restless leg syndrome, irritable bowel syndrome, irritable bladder syndrome, cognitive dysfunction, cold intolerance, multiple sensitivities and dizziness. ⋯ The results demonstrate that sensory disorders processing at a central level are in part involved in fibromyalgia. These findings also influence the management of the disease with the tendency to a multidisciplinary therapeutical concept.
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Wien Med Wochenschr · Jan 1999
Review[Psychological treatment aspects of chronic pelvic pain in the woman].
Pelvic pain is one of the most frequent disorders in gynecological practice often without clinical evidence. There are many underlying factors which contribute to this disorder, psychological as well as somatic. In the Department of Obstetrics and Gynecology at the University Hospital Graz, the diagnosis of chronic pelvic pain patients includes a medical as well as a psychological evaluation. ⋯ Chronic pelvic pain is a complex syndrome where medical and psychological diagnostic evaluation is essential. Psychological interventions can be performed at an earlier stage, in order to prevent the pain from becoming a chronic problem. The presence of psychologists within the Gynecology Department may help to establish a multidisciplinary treatment for these patients.
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Wien Med Wochenschr · Jan 1999
Review[Value of mistletoe lectin standardized mistletoe extract for evaluating antitumor properties].
It could be shown from several experiments that carbohydrate-binding mistletoe lectins represent the pharmacologically active constituents of mistletoe extracts. On the basis of these findings, it was possible to develop an extract preparation standardized with respect to the mistletoe lectin concentration. This drug is the first mistletoe preparation that fulfills the criteria of the guidelines for the development of drugs (1) regarding its quality and stability of the active ingredients under certain storage conditions. The quality of this preparation has also been shown in several animal models to demonstrate antitumoral potencies.
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Sea-biological basic knowledge for divers is offered only in special lessons for advanced scuba divers. According to statistics, however, five per cent of the deadly diving accidents are caused by underwater organisms. This number could be reduced to a fraction, by correct behaviour during the dive and after an accident. ⋯ Conidae (cone shells), Tridocna (giant clam), octopoda (octopus), 4. Acanthaster planci (crown of thorns), Echinodea (sea urchins), Holothurioidea (sea cucumber), 5. Selachoidei (shark), Batoidei (Ray), Muraenidae (moray), Plotosidae (barbel eels), Synanciidae (stonefish), Scorpaenidae (scorpionfish), Pterois (lion fish), Sphyraena Spec. (barracuda), Balistidae (triggerfish), Ostracionidae (puffer).